Short-lived Options

Today, patients who need cardiovascular replacements and access grafts suffer repeated procedures, complications or take long-term medication, because current options have severe limitations.

This is especially evident in patients who need artificial heart valves, coronary artery bypass grafts and hemodialysis access grafts.

Cardiovascular disease – CVD

#0
killer globally
0 million
deaths annually
0%
of all global deaths

Chronic kidney disease – CKD

0%
of global population affected

Growing prevalence due to CVD
(diabetes, hypertension, obesity)

Accounting for more deaths than breast and prostate cancers combined

Artificial heart valves
Artificial vessels – coronary bypass grafts
Artificial vessels – hemodialysis access grafts

Natural cardiovascular restoration

Xeltis’ devices naturally evolve into living blood vessels or heart valves, when colonized by patient’s own tissue.

This therapeutic process is called Endogenous Tissue Restoration, or ETR.

Xeltis’ restorative technology is the world’s most advanced polymer-based technology platform for cardiovascular restoration – through ETR.

ETR

Endogenous Tissue Restoration (ETR) is a new therapeutic approach, enabling the patient’s own body to naturally restore a new blood vessel or heart valve.

With ETR, the patient’s natural healing system develops tissue that pervades Xeltis’ device, forming a new, natural and fully functional blood vessel or heart valve within it. As ETR occurs, Xeltis implants are gradually absorbed by the body.

ETR is enabled by bioabsorbable polymers based on Nobel Prize awarded science.

ETR In Action

Watch ETR video now
01

Xeltis devices work as normal heart valves or blood vessels once implanted.

ENDOGENOUS TISSUE RESTORATION
02

New tissue forms around and inside the device to develop a new, living, heart valve or blood vessel.

NEOTISSUE FORMATION - ENDOGENOUS TISSUE RESTORATION (ETR)
03

Xeltis devices absorb over time, leaving patients with a natural, healthy and functioning heart valve or blood vessel.

FUNCTIONAL RESTORATION - ENDOGENOUS TISSUE RESTORATION (ETR)
Free-from • in vitro tissue engineering • stem cells • biological agents • animal tissue

Free-From

  • in vitro tissue engineering
  • stem cells
  • biological agents
  • animal tissue
Electrospinning supramolecular polymers using electric charge to draw supramolecular polymer solutions into threads that measure a fraction of the diameter of a hair.

Electrospinning supramolecular polymers

using electric charge to draw supramolecular polymer solutions into threads that measure a fraction of the diameter of a hair.

40+ international patent families portfolio protecting Xeltis’ innovative supramolecular polymer platform and its electrospinning methodology for device manufacturing.

40+ international patent families

portfolio protecting Xeltis’ innovative supramolecular polymer platform and its electrospinning methodology for device manufacturing.

Millions of patients with conditions requiring restoration of blood vessels or heart valves potentially addressed with Xeltis cardiovascular technology.

Millions of patients

with conditions requiring restoration of blood vessels or heart valves potentially addressed with Xeltis cardiovascular technology.