Endogenous tissue restoration in a hemodialysis conduit: Performance and safety after 1-year of follow-up Clinical Publications

Endogenous tissue restoration in a hemodialysis conduit: Performance and safety after 1-year of follow-up

The Journal of Vascular Access. aXess FIH 12m follow-up & clinical histopathology Abstract Background: Xeltis’ aXess hemodialysis (HD) conduit is…

Content TeamNovember 21, 2025

Computational modeling of endogenous tissue restoration in biodegradable implants Scientific Publications

Computational modeling of endogenous tissue restoration in biodegradable implants

Computers in Biology and Medicine. ETR computational modeling validated with Xeltis sheep data

Content TeamSeptember 1, 2025

Histological assessment of a novel restorative coronary artery bypass graft in a chronic ovine model Scientific Publications

Histological assessment of a novel restorative coronary artery bypass graft in a chronic ovine model

Frontiers in Bioengineering and Biotechnology. XABG 12 months sheep histology

Content TeamFebruary 10, 2025

One-year patency of a novel biorestorative polymeric coronary artery bypass conduit Clinical Publications

One-year patency of a novel biorestorative polymeric coronary artery bypass conduit

Interdisciplinary CardioVascular and Thoracic Surgery. XABG Clinical Case report 1 year patency

Content TeamJanuary 11, 2025

First-in-human feasibility study of the aXess graft (aXess-FIH): 6-Month results Clinical Publications

First-in-human feasibility study of the aXess graft (aXess-FIH): 6-Month results

The Journal of Vascular Access. aXess FIH 6 months follow-up

Content TeamFebruary 5, 2024

The effect of chronic kidney disease on tissue formation of in situ tissue-engineered vascular grafts Scientific Publications

The effect of chronic kidney disease on tissue formation of in situ tissue-engineered vascular grafts

APL Bioengineering. CKD rat aorta model: ETR not impaired by disease

Content TeamMay 23, 2023

Study protocol of a prospective single-arm multicenter clinical study to assess the safety and performance of the aXess hemodialysis graft: The pivotal study Clinical Publications

Study protocol of a prospective single-arm multicenter clinical study to assess the safety and performance of the aXess hemodialysis graft: The pivotal study

The Journal of Vascular Access. Study Protocol of aXess pivotal clinical trial

Content TeamMay 10, 2023

1-Year Patency of Biorestorative Polymeric Coronary Artery Bypass Grafts in an Ovine Model Scientific Publications

1-Year Patency of Biorestorative Polymeric Coronary Artery Bypass Grafts in an Ovine Model

JACC: Basic to Translational Science. XABG pre-clinical 1 year follow-up in sheep

Content TeamNovember 9, 2022

Supramolecular Biomaterials in the Netherlands Scientific Publications

Supramolecular Biomaterials in the Netherlands

Tissue Engineering Part A. State-of-the-art review Supramolecular Biomaterials NL

Content TeamJune 16, 2022

Marker-Independent Monitoring of in vitro and in vivo Degradation of Supramolecular Polymers Applied in Cardiovascular in situ Tissue Engineering Scientific Publications

Marker-Independent Monitoring of in vitro and in vivo Degradation of Supramolecular Polymers Applied in Cardiovascular in situ Tissue Engineering

Frontiers in Cardiovascular Medicine. Vascular graft preclinical, 1year follow-up carotid in sheep – deep insights using Raman spectroscopy

Content TeamMay 17, 2022

Supramolecular Polymer materials Bring Restorative Heart Valve Therapy to Patients Scientific Publications

Supramolecular Polymer materials Bring Restorative Heart Valve Therapy to Patients

Materials Today. Xeltis Technology review paper, focus on heart valve application

Content TeamJanuary 31, 2022

Chronic Hemodynamic Performance of a Biorestorative Transcatheter Heart Valve in an Ovine Model Scientific Publications

Chronic Hemodynamic Performance of a Biorestorative Transcatheter Heart Valve in an Ovine Model

EuroIntervention. Transcatheter Aortic Valve 1 year follow-up in sheep

Content TeamDecember 17, 2021

Inflammatory and regenerative processes in bioresorbable synthetic pulmonary valves up to two years in sheep: Spatiotemporal insights augmented by Raman microspectroscopy Scientific Publications

Inflammatory and regenerative processes in bioresorbable synthetic pulmonary valves up to two years in sheep: Spatiotemporal insights augmented by Raman microspectroscopy

Acta Biomaterialia. PV preclinical: Deep mechanistic study on spatiotemporal ETR insights in Xeltis sheep PV up to 2 years

Content TeamNovember 1, 2021

Tissue response, macrophage phenotype, and intrinsic calcification induced by cardiovascular biomaterials: Can clinical regenerative potential be predicted in a rat subcutaneous implant model? Scientific Publications

Tissue response, macrophage phenotype, and intrinsic calcification induced by cardiovascular biomaterials: Can clinical regenerative potential be predicted in a rat subcutaneous implant model?

Journal of Biomedical Materials Research Part A. ETR preclinical: Mechanistic study with Dr. Badylak on positive remodeling with Xeltis materials

Content TeamJuly 29, 2021

A Novel Restorative Pulmonary Valve Conduit: Early Outcomes of Two Clinical Trials Clinical Publications

A Novel Restorative Pulmonary Valve Conduit: Early Outcomes of Two Clinical Trials

Frontiers in Cardiovascular Medicine. Pulmonary Valve clinical Xplore-1 & Xplore-2 1 year follow-up

Content TeamMarch 4, 2021

Total cavopulmonary connection with a new restorative vascular graft: results at 2 years Clinical Publications

Total cavopulmonary connection with a new restorative vascular graft: results at 2 years

Journal of Thoracic Disease. Fontan clinical 2 years follow-up

Content TeamAugust 20, 2020

Morphology and mechanisms of a novel absorbable polymeric conduit in the pulmonary circulation of sheep Scientific Publications

Morphology and mechanisms of a novel absorbable polymeric conduit in the pulmonary circulation of sheep

Cardiovascular Pathology. Pulmonary conduit preclinical 1 year follow-up in sheep

Content TeamJanuary 31, 2019

A novel restorative pulmonary valved conduit in a chronic sheep model: Mid-term hemodynamic function and histologic assessment Scientific Publications

A novel restorative pulmonary valved conduit in a chronic sheep model: Mid-term hemodynamic function and histologic assessment

J Thorac Cardiovasc Surg. Pulmonary valve preclinical 1 year follow-up in sheep

Content TeamJune 20, 2018

Restorative valve therapy by endogenous tissue restoration: tomorrow’s world? Reflection on the EuroPCR 2017 session on endogenous tissue restoration Scientific Publications

Restorative valve therapy by endogenous tissue restoration: tomorrow’s world? Reflection on the EuroPCR 2017 session on endogenous tissue restoration

EuroIntervention. Endogenous Tissue Restoration. Background & KOL perspective

Content TeamSeptember 24, 2017

Total cavopulmonary connection with a new bioabsorbable vascular graft: First clinical experience Clinical Publications

Total cavopulmonary connection with a new bioabsorbable vascular graft: First clinical experience

J Thorac Cardiovasc Surg. Fontan clinical 1 year follow-up

Content TeamJune 20, 2017

Supramolecular biomaterials Scientific Publications

Supramolecular biomaterials

Nature Materials. High impact review on supramolecular biomaterials used by Xeltis

Content TeamDecember 18, 2015

Functional supramolecular polymers Scientific Publications

Functional supramolecular polymers

Science. High impact review on supramolecular polymers used by Xeltis

Content TeamFebruary 12, 2012

Supramolecular polymers at work Scientific Publications

Supramolecular polymers at work

Materials Today. High impact paper reviewing broad polymer platform used by Xeltis

Content TeamApril 20, 2004

Reversible Polymers Formed from Self-Complementary Monomers Using Quadruple Hydrogen Bonding Scientific Publications

Reversible Polymers Formed from Self-Complementary Monomers Using Quadruple Hydrogen Bonding

Science. High impact paper introducing chemistry used by Xeltis

Content TeamNovember 28, 1997

Supramolecular Chemistry—Scope and Perspectives Molecules, Supermolecules, and Molecular Devices Scientific Publications

Supramolecular Chemistry—Scope and Perspectives Molecules, Supermolecules, and Molecular Devices

Angewandte Chemie. Nobel prize Lecture JM Lehn

Content TeamJanuary 10, 1988

Computational modeling of endogenous tissue restoration in biodegradable implants Scientific Publications

Computational modeling of endogenous tissue restoration in biodegradable implants

Computers in Biology and Medicine. ETR computational modeling validated with Xeltis sheep data

Content TeamSeptember 1, 2025

Histological assessment of a novel restorative coronary artery bypass graft in a chronic ovine model Scientific Publications

Histological assessment of a novel restorative coronary artery bypass graft in a chronic ovine model

Frontiers in Bioengineering and Biotechnology. XABG 12 months sheep histology

Content TeamFebruary 10, 2025

The effect of chronic kidney disease on tissue formation of in situ tissue-engineered vascular grafts Scientific Publications

The effect of chronic kidney disease on tissue formation of in situ tissue-engineered vascular grafts

APL Bioengineering. CKD rat aorta model: ETR not impaired by disease

Content TeamMay 23, 2023

1-Year Patency of Biorestorative Polymeric Coronary Artery Bypass Grafts in an Ovine Model Scientific Publications

1-Year Patency of Biorestorative Polymeric Coronary Artery Bypass Grafts in an Ovine Model

JACC: Basic to Translational Science. XABG pre-clinical 1 year follow-up in sheep

Content TeamNovember 9, 2022

Supramolecular Biomaterials in the Netherlands Scientific Publications

Supramolecular Biomaterials in the Netherlands

Tissue Engineering Part A. State-of-the-art review Supramolecular Biomaterials NL

Content TeamJune 16, 2022

Marker-Independent Monitoring of in vitro and in vivo Degradation of Supramolecular Polymers Applied in Cardiovascular in situ Tissue Engineering Scientific Publications

Marker-Independent Monitoring of in vitro and in vivo Degradation of Supramolecular Polymers Applied in Cardiovascular in situ Tissue Engineering

Frontiers in Cardiovascular Medicine. Vascular graft preclinical, 1year follow-up carotid in sheep – deep insights using Raman spectroscopy

Content TeamMay 17, 2022

Supramolecular Polymer materials Bring Restorative Heart Valve Therapy to Patients Scientific Publications

Supramolecular Polymer materials Bring Restorative Heart Valve Therapy to Patients

Materials Today. Xeltis Technology review paper, focus on heart valve application

Content TeamJanuary 31, 2022

Chronic Hemodynamic Performance of a Biorestorative Transcatheter Heart Valve in an Ovine Model Scientific Publications

Chronic Hemodynamic Performance of a Biorestorative Transcatheter Heart Valve in an Ovine Model

EuroIntervention. Transcatheter Aortic Valve 1 year follow-up in sheep

Content TeamDecember 17, 2021

Inflammatory and regenerative processes in bioresorbable synthetic pulmonary valves up to two years in sheep: Spatiotemporal insights augmented by Raman microspectroscopy Scientific Publications

Inflammatory and regenerative processes in bioresorbable synthetic pulmonary valves up to two years in sheep: Spatiotemporal insights augmented by Raman microspectroscopy

Acta Biomaterialia. PV preclinical: Deep mechanistic study on spatiotemporal ETR insights in Xeltis sheep PV up to 2 years

Content TeamNovember 1, 2021

Tissue response, macrophage phenotype, and intrinsic calcification induced by cardiovascular biomaterials: Can clinical regenerative potential be predicted in a rat subcutaneous implant model? Scientific Publications

Tissue response, macrophage phenotype, and intrinsic calcification induced by cardiovascular biomaterials: Can clinical regenerative potential be predicted in a rat subcutaneous implant model?

Journal of Biomedical Materials Research Part A. ETR preclinical: Mechanistic study with Dr. Badylak on positive remodeling with Xeltis materials

Content TeamJuly 29, 2021

Endogenous tissue restoration in a hemodialysis conduit: Performance and safety after 1-year of follow-up Clinical Publications

Endogenous tissue restoration in a hemodialysis conduit: Performance and safety after 1-year of follow-up

The Journal of Vascular Access. aXess FIH 12m follow-up & clinical histopathology Abstract Background: Xeltis’ aXess hemodialysis (HD) conduit is…

Content TeamNovember 21, 2025

One-year patency of a novel biorestorative polymeric coronary artery bypass conduit Clinical Publications

One-year patency of a novel biorestorative polymeric coronary artery bypass conduit

Interdisciplinary CardioVascular and Thoracic Surgery. XABG Clinical Case report 1 year patency

Content TeamJanuary 11, 2025

First-in-human feasibility study of the aXess graft (aXess-FIH): 6-Month results Clinical Publications

First-in-human feasibility study of the aXess graft (aXess-FIH): 6-Month results

The Journal of Vascular Access. aXess FIH 6 months follow-up

Content TeamFebruary 5, 2024

Study protocol of a prospective single-arm multicenter clinical study to assess the safety and performance of the aXess hemodialysis graft: The pivotal study Clinical Publications

Study protocol of a prospective single-arm multicenter clinical study to assess the safety and performance of the aXess hemodialysis graft: The pivotal study

The Journal of Vascular Access. Study Protocol of aXess pivotal clinical trial

Content TeamMay 10, 2023

A Novel Restorative Pulmonary Valve Conduit: Early Outcomes of Two Clinical Trials Clinical Publications

A Novel Restorative Pulmonary Valve Conduit: Early Outcomes of Two Clinical Trials

Frontiers in Cardiovascular Medicine. Pulmonary Valve clinical Xplore-1 & Xplore-2 1 year follow-up

Content TeamMarch 4, 2021

Total cavopulmonary connection with a new restorative vascular graft: results at 2 years Clinical Publications

Total cavopulmonary connection with a new restorative vascular graft: results at 2 years

Journal of Thoracic Disease. Fontan clinical 2 years follow-up

Content TeamAugust 20, 2020

Total cavopulmonary connection with a new bioabsorbable vascular graft: First clinical experience Clinical Publications

Total cavopulmonary connection with a new bioabsorbable vascular graft: First clinical experience

J Thorac Cardiovasc Surg. Fontan clinical 1 year follow-up

Content TeamJune 20, 2017